GLP-2 TIRZ

Tirzepatide (GLP-1/GIP Receptor Agonist) – LY3298176

Product Overview

Tirzepatide is a first-in-class, dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Engineered from the native GIP peptide backbone, it represents a significant structural advancement in metabolic research compounds. By simultaneously activating two critical incretin pathways, Tirzepatide is utilized in advanced studies to observe synergistic effects on glycemic control, energy expenditure, and lipid metabolism.

Technical Specifications

• Molecular Formula: C225H348N48O68

• Molecular Weight: 4813.45 g/mol

• CAS Number: 2023788-19-2

• Sequence Profile: 39-amino acid peptide featuring a C20 fatty diacid moiety attached via a glutamic acid spacer, with Aib substitutions for enzymatic resistance.
  

Mechanism of Action

Tirzepatide is uniquely engineered to provide balanced GIP and GLP-1 receptor engagement, yielding complementary metabolic effects:

• GIP Receptor Agonism: Enhances glucose-dependent insulin secretion, promotes adipose tissue lipid storage, regulates adipokine secretion, and potentiates central appetite suppression.

• GLP-1 Receptor Agonism: Suppresses glucagon release, further supports insulin secretion, slows gastric emptying, and centrally regulates hunger and satiety.

• Pharmacokinetic Optimization: The addition of a C20 fatty diacid chain enables high-affinity albumin binding, significantly extending the terminal half-life to allow for a prolonged, once-weekly circulating depot.

🚚 📦 Availability 

At CNL, we believe quality is worth the wait. Instead of stocking products and have them sit for months, most orders are produced in small batches to maintain the quality and consistency our customers expect.

Production typically takes approximately two weeks. While this isn't the norm in today's world of overnight delivery, it's how we deliver the premium quality we're known for.

Limited inventory may be available for immediate shipment after large production runs or special promotions.

As a thank you for your patience, we offer bundle discounts of up to 50% OFF.

⚠️ Important Disclaimer for Carbon Nova Labs Customers: All information provided is for educational and reference purposes only. Tirzepatide is sold strictly for laboratory research use only. This compound is not approved by the FDA for human consumption, therapeutic use, or clinical application. Ensure compliance with all institutional safety protocols and consult qualified professionals before conducting research.