Ipamorelin (Selective Growth Hormone Secretagogue) – NNC 26-0161

Product Overview

Ipamorelin is an advanced, synthetic pentapeptide recognized as the first truly selective growth hormone secretagogue (GHRP). Engineered to act as a highly specific agonist at the ghrelin receptor (GHSR-1a), it stimulates a robust, pulsatile release of endogenous growth hormone from the pituitary gland. Unlike earlier generations of GHRPs, Ipamorelin provides a uniquely "clean" release profile, elevating growth hormone without meaningfully raising off-target stress hormones like cortisol, prolactin, or ACTH, making it an exceptional tool for isolated endocrinology and metabolic research.

Technical Specifications

• Molecular Formula: C38H49N9O5

• Molecular Weight: 711.85 g/mol

• CAS Number: 170851-70-4

• Sequence Profile: Aib-His-D-2-Nal-D-Phe-Lys-NH2

Mechanism of Action

Ipamorelin exerts its highly targeted effects by mimicking the natural hormone ghrelin, but with superior selectivity:

• GHSR-1a Activation: Binds directly to the growth hormone secretagogue receptor in the pituitary gland, triggering intracellular calcium release and GH granule exocytosis.

• Pulsatile Mimicry: Rather than forcing an unnatural, continuous elevation of GH that causes rapid receptor desensitization, Ipamorelin creates a discrete GH pulse that mimics the amplitude and duration of natural, endogenous secretory episodes, preserving vital feedback loop regulation.

• The Selectivity Advantage: It completely avoids the catabolic and immunosuppressive side effects associated with cortisol elevation, the gynecomastia concerns linked to prolactin, and the intense appetite-stimulating (ghrelin-mimetic) surges seen with compounds like GHRP-6.

🚚 📦 Availability 

At CNL, we believe quality is worth the wait. Instead of stocking products and have them sit for months, most orders are produced in small batches to maintain the quality and consistency our customers expect.

Production typically takes approximately two weeks. While this isn't the norm in today's world of overnight delivery, it's how we deliver the premium quality we're known for.

Limited inventory may be available for immediate shipment after large production runs or special promotions.

As a thank you for your patience, we offer bundle discounts of up to 50% OFF.

⚠️ Important Disclaimer for Carbon Nova Labs Customers: All information provided is for educational and reference purposes only. Ipamorelin is sold strictly for laboratory research use only. This compound is not approved by the FDA for human consumption, therapeutic use, or clinical application. Ensure compliance with all institutional safety protocols and consult qualified professionals before conducting research.