Pinealon

Pinealon – Synthetic Tripeptide Bioregulator

At a Glance: Pinealon is a short, synthetic tripeptide (composed of just three amino acids: Glutamate, Aspartate, and Arginine) classified as an ultrashort peptide bioregulator. What it is used for: It is utilized in advanced laboratory research to study neuroprotection, cognitive enhancement, and circadian rhythm optimization. By directly targeting brain and pineal gland tissue, researchers study its ability to protect lab rat models from severe oxidative stress, preserve memory networks, and restore youthful sleep-wake cycles at the genetic level.

Product Overview

Pinealon (EDR) is a highly specialized neuroprotective compound originally developed by researchers studying the pineal gland and age-related cognitive decline. Because it is an ultrashort peptide, it possesses the rare biological ability to easily cross the blood-brain barrier. Rather than simply masking symptoms or temporarily stimulating neurotransmitters like a traditional nootropic, Pinealon acts as a "cytomedine" or bioregulator. It physically enters neuronal cells to interact with DNA, modulating gene expression to repair structural damage, clear neurotoxins, and support long-term neuronal survival in stressed or aging research subjects.

Technical Specifications

• Molecular Formula: C15H26N6O8

• Molecular Weight: 418.40 g/mol

• CAS Number: 175175-23-2

• Sequence Profile: Glu-Asp-Arg (E-D-R)

Mechanism of Action

Pinealon initiates profound neurological healing by operating through epigenetic regulation and targeted cellular defense:

• Direct Gene Modulation: Binds directly to specific promoter regions of DNA within neurons. This sequence-specific binding upregulates the transcription of genes responsible for cellular repair, effectively "waking up" the cell's natural maintenance pathways.

• Oxidative Stress Neutralization: Drastically reduces the accumulation of reactive oxygen species (ROS) in brain tissue. By defending against oxidative insults, it protects delicate synaptic connections from degrading during periods of extreme metabolic stress or hypoxia.

• Anti-Apoptotic Cellular Maintenance: Prevents premature programmed cell death (apoptosis) in vulnerable neuronal networks. It physically maintains the integrity of dendritic spines (the structures responsible for memory retention), extending the functional lifespan of the brain's processing centers.

• Circadian & Pineal Optimization: Mimics natural regulatory signals to the pineal gland, helping to synchronize endogenous melatonin production and correct dysfunctional circadian rhythms independent of exogenous hormone administration.

Primary Research Applications

Pinealon is a vital compound for in vitro and animal model studies focusing on:

• Age-related cognitive decline, spatial memory retention, and brain fog

• Circadian rhythm dysfunction and sleep-wake cycle normalization

• Traumatic Brain Injury (TBI), stroke recovery, and neuroinflammation

• Oxidative stress damage models and neurodegenerative pathologies

Storage & Handling

For optimal stability and structural integrity, store the lyophilized powder at -4°F (-20°C). Once reconstituted, store at 36°F to 46°F (2°C to 8°C), sealed tightly, and strictly protect from moisture and light.

⚠️ Important Disclaimer for Carbon Nova Labs Customers: All information provided is for educational and reference purposes only. Pinealon is sold strictly for laboratory research use only. This compound is not approved by the FDA for human consumption, therapeutic use, or clinical application. Ensure compliance with all institutional safety protocols and consult qualified professionals before conducting research.