PT-141

PT-141 (Bremelanotide) – Melanocortin Agonist

At a Glance: PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide and a non-selective agonist of the melanocortin receptors (primarily MC3R and MC4R). What it is used for: It is utilized in laboratory research to study the neurological pathways governing sexual arousal, libido, and erectile function. Unlike vascular-focused treatments, it acts directly on the central nervous system to stimulate sexual response in both male and female models.

Product Overview

PT-141 is a synthetic peptide derivative of alpha-melanocyte-stimulating hormone (alpha-MSH). Developed initially from the peptide Melanotan II, PT-141 was specifically isolated to study its profound effects on sexual arousal without inducing significant melanogenesis (tanning). By directly targeting the central nervous system rather than the cardiovascular system, it represents a pivotal compound for researching psychogenic and neurologically driven sexual dysfunction.

Technical Specifications

• Molecular Formula: C50H68N14O10

• Molecular Weight: 1025.18 g/mol

• CAS Number: 189691-06-3

• Sequence Profile: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Mechanism of Action

PT-141 initiates biological effects by acting directly on the central nervous system rather than the vascular system:

• MC4R Agonism: Strongly activates the Melanocortin-4 receptor in the hypothalamus, which is the primary neurological pathway linked to initiating sexual desire, arousal, and erectile responses.

• MC3R Agonism: Activates the Melanocortin-3 receptor, contributing to energy homeostasis and complementary central nervous system responses.

• Neurological Pathway Activation: Bypasses peripheral vasculature to directly stimulate the brain, inducing behavioral and physiological sexual responses independent of blood pressure manipulation.

🚚 📦 Availability 

At CNL, we believe quality is worth the wait. Instead of stocking products and have them sit for months, most orders are produced in small batches to maintain the quality and consistency our customers expect.

Production typically takes approximately two weeks. While this isn't the norm in today's world of overnight delivery, it's how we deliver the premium quality we're known for.

Limited inventory may be available for immediate shipment after large production runs or special promotions.

As a thank you for your patience, we offer bundle discounts of up to 50% OFF.

⚠️ Important Disclaimer for Carbon Nova Labs Customers: All information provided is for educational and reference purposes only. PT-141 is sold strictly for laboratory research use only. This compound is not approved by the FDA for human consumption, therapeutic use, or clinical application. Ensure compliance with all institutional safety protocols and consult qualified professionals before conducting research.